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Monitoring of minimal residual disease using WT1 assay for patients with chronic myeloid leukemia who undergo allogeneic stem cell transplantation

โœ Scribed by Tamaki, H; Ogawa, H


Book ID
110014280
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
71 KB
Volume
34
Category
Article
ISSN
0007-1188

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Both WT1 and PRAME are highly expressed in acute myeloid leukemia (AML) patients. To assess the efficacy of their simultaneous detection for the purpose of monitoring minimal residual disease (MRD), we used real-time quantitative RT-PCR to quantify both WT1 and PRAME transcript levels in the bone ma