Long term ursodeoxycholic acid (URSO) treatment improves glutathione status in primary biliary cirrhosis (PBC)
β Scribed by Philip Pemberton; Ali Aboutwerat; Alexander Smith; Sanjiv Jain; Ian Laing; Edward Mather; Thomas Warnes
- Book ID
- 118565478
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 229 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0168-8278
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π SIMILAR VOLUMES
Primary biliary cirrhosis (PBC) is a progressive cholestatic liver disease frequently leading to development of cirrhosis and its complications. Ursodeoxycholic acid (UDCA) is a beneficial medical therapy for patients with PBC. Improvement in some histological features, but not in histological stage
Biochemical response to ursodeoxycholic acid (UDCA) in patients with primary biliary cirrhosis (PBC) is variable. It has been recently proposed that an alkaline phosphatase (ALP) decline of more than 40% in baseline value or a normal level after 1 year of UDCA treatment (Barcelona criteria) could se
We read with interest the article by Corpechot et al. in a recent issue of HEPATOLOGY. 1 Corpechot et al. identify the absence of a biochemical response to ursodeoxycholic acid (UDCA) as an important predictive factor for death or liver transplantation in patients with primary biliary cirrhosis (PBC
The recurrence of primary biliary cirrhosis (PBC) in the hepatic allograft may impact patient and graft survival with long-term follow-up. The efficacy of ursodeoxycholic acid (UDCA) for treatment of recurrent PBC after liver transplantation (LT) remains less well known. The aims of this study were