Long-term treatment with low doses of interleukin-2 and interferon-α: immunological effects in advanced renal cell cancer
✍ Scribed by Laura Pavone; Simeone Andrulli; Rosaria Santi; Maria Majori; Carlo Buzio
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 184 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0340-7004
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## Background: The goal of the current report was to demonstrate the long-term efficacy of outpatient subcutaneous (sc) interferon alpha (ifn-alpha) and sc interleukin 2 (il-2)-based combination regimens in patients with metastatic renal cell carcinoma. ## Methods: In three consecutive clinical t
Thirty patients with advanced renal cell carcinoma (RCC), 23 of whom had distant metastases in at least one organ, were entered after nephrectomy into a protocol involving vaccination with Newcastle disease virus (NDV)-modified autologous tumour material, with a subsequent induction week and repetit