The combined administration of subcutaneous recombinant human interleukin-2 (rIL-2) and interferon-a (rIFN-~) was studied in a phase II trial on patients with advanced progressive renal cell cancer. Safety, tolerance and clinical response rate of this outpatient treatment protocol were assessed in 2
✦ LIBER ✦
A phase II study of interferon α and low-dose subcutaneous interleukin-2 in advanced renal cell carcinoma
✍ Scribed by A. Piga; Paolo Giordani; Agata Quattrone; Marco Giulioni; Giorgio De Signoribus; Stefania Antognoli; Riccardo Cellerino
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 72 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0340-7004
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## Abstract ## BACKGROUND The objective of this study was to determine the response rate and toxicity of gemcitabine and continuous‐infusion 5‐fluorouracil (5‐FU) in combination with subcutaneous interleukin‐2 (IL2) and interferon‐α (IFNA) in patients with metastatic renal cell carcinoma. ## METH