The exact risk of developing a second primary cancer following radiotherapy for testicular seminoma is not known. At the Northern Israel Oncology Center, between the years 1968-1988, 75 patients with early stage (1,IIA) testicular seminoma were treated by orchiectomy followed by radiation therapy. T
Long-term survival in patients treated for testicular seminoma
β Scribed by Yusef Hannun; Davor Vugrin
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 382 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-4790
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β¦ Synopsis
Abstract
Fortyβeight patients with newlyβdiagnosed testicular seminomas were followed for a mean of 7 years after treatment. At the time of diagnosis, seminoma was confined to testis in 74% (36) and was metastatic to retroperitoneal lymph nodes in 15% (7) and to distant nodal sites or parenchymal organs in 10% (5). Ninetyβsix percent remained free of disease, 94% in first complete remission (CR) and 2% after treatment of first recurrence. Longβterm diseaseβfree survival in CR per stage was 97% (35/36) for Stage I, 100% for Stage II, and 80% (4/5) for Stage III. However, three patients, who received prior chest radiation therapy (RT), died from acute myocardial infarction 2, 9, and 10 years after treatment and while free of disease.
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