Long-term survival in patients operated on for benign peptic ulcer disease

Markers for type II collagen breakdown p

Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritis

✍ Robert Landewé; Piet Geusens; Maarten Boers; Désirée van der Heijde; Willem Lems 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 1 views

## Abstract ## Objective To investigate in a randomized clinical trial setting with an aggressive combination‐therapy arm and a mild‐monotherapy arm, whether therapy‐induced changes in urinary C‐terminal crosslinking telopeptide of type I collagen (CTX‐I) and type II collagen (CTX‐II) predict 5‐ye