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Long-Term Survival and Function of Intraportal Porcine and Human Islet Xenografts in Nondiabetic Nude Mice

✍ Scribed by B.Y. Xu; Y. Yu; I.H. Al-Abdullah; F. Kandeel; B. Hering; J.R. Wright Jr


Book ID
116934044
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
986 KB
Volume
40
Category
Article
ISSN
0041-1345

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## Abstract This study was performed to observe the long‐term effect of FTY720 on lymphocyte count change and islet allograft survival. Diabetic C57BL/6 mice were given FTY720 (group 1, 0.5 mg/kg/day; group 2, 1.0 mg/kg/day) or its vehicle (group 3, controls) after transplantation. Median graft sur