## Background: For patients treated with combination resection and postoperative radiotherapy, the interval between surgery and completion of radiotherapy represents an opportunity for tumor repopulation and treatment failure. a prospective trial to test the feasibility and efficacy of accelerated
Long-Term Results of a Phase III Randomized Trial of Postoperative Radiotherapy With or Without Carboplatin in Patients With High-Risk Head and Neck Cancer
β Scribed by Athanassios Argiris; Michalis V. Karamouzis; Jonas T. Johnson; Dwight E. Heron; Eugene Myers; David Eibling; Elmer Cano; Susan Urba; Jack Gluckman; Jennifer R. Grandis; Yun Wang; Sanjiv S. Agarwala
- Book ID
- 110089121
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 141 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0023-852X
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## Abstract ## BACKGROUND: A randomized phase 2 study was performed to investigate the efficacy/toxicity of combining concomitant boost radiation and weekly carboplatin/paclitaxel with or without amifostine in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). ##