Patterns of failure and long-term results in high-risk resected gastric cancer treated with postoperative radiotherapy with or without intraoperative electron boost
✍ Scribed by Martínez-Monge, Rafael; Calvo, Felipe A.; Azinovic, Ignacio; Aristu, Jose Javier; Hernández, Jose Luis; Pardo, Fernando; Fernández, Pablo; García-Foncillas, Jesús; Alvarez-Cienfuegos, Javier
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 60 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0022-4790
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✦ Synopsis
Background:
To evaluate the possible role of adjuvant radiotherapy in the management of high-risk resected gastric carcinoma.
Methods:
From 1982 to 1993, 62 patients surgically resected of a primary gastric cancer with adverse pathological features (serosal and/or regional lymph node involvement) were treated with postoperative radiotherapy with (group i) or without (group ii) intraoperative electron boost to the surgical bed and coeliac axis (iort).
Results:
After a median follow-up of 75.6 months (range 4-120+) for iort patients and 91.2 months (range 6-149+) for non-iort patients, overall relapse rates for group i and group ii patients were 44.5% and 48.6% and local-regional relapse rates were 11.1% and 20%, respectively. actuarial survival rates projected at the maximum follow-up were 41% and 38% in groups i and ii, respectively.
Conclusions:
This retrospective analysis suggests a beneficial effect of adjuvant external radiotherapy in promoting local-regional control in high-risk resected gastric cancer.