Long-term outcome of salvage high-dose chemotherapy in patients with germ cell tumor with poor prognostic features
β Scribed by Ugo De Giorgi; Giovanni Rosti; Roberto Salvioni; Giorgio Papiani; Michela Ballardini; Giorgio Pizzocaro; Maurizio Marangolo
- Book ID
- 116956550
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 524 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1078-1439
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## Abstract ## BACKGROUND Highβdose chemotherapy (HDCT) followed by hematopoietic stem cell support (HSCS) potentially may be curative in patients with germ cell tumor (GCT) who develop recurrent tumors or who have an inadequate response after receiving standardβdose chemotherapy. The authors repo
## BACKGROUND. The optimal treatment of patients with recurrent or refractory germ
Forty-four patients with nonseminomatous germ cell tumors with "poor prognostic features" were entered on the VAB-5 regimen and 38 are evaluable. VAB-5 represents an intensified version of the VAB-4 protocol. Poor prognostic features were considered to be bulky metastases (>5 cm in diameter), palpab