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Long-term effects of acetazolamide and sodium chloride loading on cisplatin nephrotoxicity in the rat

✍ Scribed by Dr. H. Th. HEIDEMANN; K. HOFFMANN; G. INSELMANN


Book ID
114726956
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
434 KB
Volume
20
Category
Article
ISSN
0014-2972

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Effects of the diuretics mannitol or ace
✍ Nahed M. Osman; Marion P. Copley; Charles L. Litterst πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 584 KB

The anticancer drug cisplatin has been known to produce severe renal lesions characterized by high levels of blood urea nitrogen (BUN), toxic nephrosis, and platinum (Pt) retention in the kidney. The effect of IV pretreatment with acetazolamide (ACZ) 30 min before or mannitol (MAN) immediately prior