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Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin a in rats

โœ Scribed by Kei Suzuki; Yoshihisa Shitara; Kousuke Fukuda; Toshiharu Horie


Book ID
112134581
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
295 KB
Volume
101
Category
Article
ISSN
0022-3549

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Intestinal lymphatic absorption of cyclo
โœ Clarence T. Ueda; Michel Lemaire; Guy Gsell; Kurt Nussbaumer ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 592 KB

The intestinal lymphatic absorption of cyclosporin A (CyA) following oral adminstration of 6.5 f0.6 and 252f 1.4mg kg-' doses of the drug dissolved in an olive oil solution was studied using a thoracic duct-cannulated rat model. Cumulative lymph samples were collected for up to 114h post-dosing and