A program, WRANL, is described for the analysis of immunoassays or bioassays which have a logistic dose-response relationship. Responses are transformed to logits and iterative weighted regression analysis is used to obtain log dose-logit response lines for all preparations compared in an assay. Pot
LOGIT: A program for dose-response analysis
โ Scribed by John Koshiver; Dan Moore
- Publisher
- Elsevier Science
- Year
- 1979
- Weight
- 273 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0010-468X
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โฆ Synopsis
We describe a FORTRAN computer program for fitting the logistic distribution function:
Where x represents dose or time, to dose-response data. The program determines both weighted least squares and maximum likelihood estimates for the parameters a and/3. It also calculates the standard errors of a and # under both estimation methods, as well as the median lethal dose (LD50) and its standard error. Dose-response curves found by both fitting methods can be plotted as well as the 95% confidence bands for these lines.
Logit analysis
Bioassay Dose-response analysis
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