✦ LIBER ✦

Two computer programs using logit transformation for the analysis of S-shaped curves

✍ Scribed by Edgar Rieger; Janet J. Bijl; Manfred Rieger

Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 702 KB
Volume: 23
Category: Article
ISSN: 0010-4825
DOI: 10.1016/0010-4825(93)90136-o

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✦ Synopsis

Two BASIC computer programs using logit transformation for the analysis of S-shaped curves are presented. The first program estimates the median effective dose (ED%) of drugs. A maximum likelihood method similar to Finney's algorithm of probit analysis is applied. The second fits S-shaped curves to empirical data which cannot be transformed easily to proportions. Logit transformation proves to be a simple and accurate alternative to probit transformation when computing memory is limited or calculation speed is critical.

Logit transformation Probit transformation n&l

Computer program Dose-response relationship

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