Two programs allowing nonlinear least-squares fits to data conforming to the onecompartment oral and the two-compartment intravenous pharmacokinetic models are described. Model parameter estimates are obtained together with an estimate of the precision of these parameters. The method is based on the
Logistic curve fitting and parameter estimation using nonlinear noniterative least-squares regression analysis
β Scribed by Anthony Ayiomamitis
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 494 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0010-4809
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β¦ Synopsis
A microcomputer program has been developed for the fitting of the logistic curve to biological, medical, and other experimental data. In addition to supplying estimates for all of the logistic curve parameters, the program provides the fitted result for each input datum thus allowing for the immediate assessment of the logistic curve and detection of possible OUtk.rS.
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