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Locked nucleic acids (LNA) and medical applications

✍ Scribed by Henrik Ørum; Andreas Wolter; Lars Kongsbak

Book ID
118805355
Publisher
Springer Netherlands
Year
2003
Tongue
English
Weight
229 KB
Volume
10
Category
Article
ISSN
1573-3149

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We have used 2D NMR spectroscopy to study the sugar conformations of oligonucleotides containing a conformationally restricted nucleotide (LNA) with a 2'-O, 4'-C-methylene bridge. We have investigated a modified 9-mer single stranded oligonucleotide as well as three 9-and 10-mer modified oligonucleo

ChemInform Abstract: LNA (Locked Nucleic
ChemInform Abstract: LNA (Locked Nucleic Acid).
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v