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FISHing with locked nucleic acids (LNA): evaluation of different LNA/DNA mixmers

✍ Scribed by Asli N Silahtaroglu; Niels Tommerup; Henrik Vissing


Book ID
117593193
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
208 KB
Volume
17
Category
Article
ISSN
0890-8508

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Ξ±-LNA (Locked Nucleic Acid with Ξ±-D-Conf
✍ Poul Nielsen; Nanna K. Christensen; Jakob K. Dalskov πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 224 KB πŸ‘ 1 views

Alpha-LNA is presented as a stereoisomer of LNA (locked nucleic acid) with alpha-D-configuration. Three different approaches towards the thymine alpha-LNA monomer as well as the 5-methylcytosine alpha-LNA monomer are presented. Different alpha-LNA sequences have been synthesised and their hybridisat