Loci of Ceric Cation Mediated Hydrolyses of Dimethyl Phosphate and Methyl Methylphosphonate

17O NMR of diastereomeric 3′,5′-cyclic t

17O NMR of diastereomeric 3′,5′-cyclic thymidine methyl phosphates, methylphosphonates, and N,N-dimethyl phosphoramidates. Phosphorus configuration of P-chiral [17O, 18O]-nucleoside phosphate diesters

✍ Alan E. Sopchik; S. Matthew Cairns; Wesley G. Bentrude 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 239 KB

Sunmary: "0 NMR spectra of the title compounds show well-separated P=O" peaks and configurationally diagnostic 6"O values and line widths. Use of these features to assign configurational purity to ("0, "0) P-chiral nucleoside monophosphate diesters is proposed. Solvent CD3CN CD3CN CD3CN CD3CN CD3CN