✦ LIBER ✦
17O NMR of diastereomeric 3′,5′-cyclic thymidine methyl phosphates, methylphosphonates, and N,N-dimethyl phosphoramidates. Phosphorus configuration of P-chiral [17O, 18O]-nucleoside phosphate diesters
✍ Scribed by Alan E. Sopchik; S. Matthew Cairns; Wesley G. Bentrude
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 239 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Sunmary: "0 NMR spectra of the title compounds show well-separated P=O" peaks and configurationally diagnostic 6"O values and line widths. Use of these features to assign configurational purity to ("0, "0) P-chiral nucleoside monophosphate diesters is proposed. Solvent CD3CN CD3CN CD3CN CD3CN CD3CN CD3CN CDC13 CDC13 Table.
170 NMR Parameters for 7-12.
T,"C d70a 80 87.7