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Location on the chromosome of Escherichia coli of genes governing purine metabolism

✍ Scribed by Jochimsen, Bjarne ;Nygaard, Per ;Vestergaard, Trygvi

Publisher: Springer
Year: 1975
Tongue: English
Weight: 582 KB
Volume: 143
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00269424

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✦ Synopsis

Genes coding for enzymes functioning in purine salvage pathways have been located on the chromosome of Escherichia coli. The gene add encoding adenosine deaminase was located by transduction at 31 min, the gene order was established to be man-uidA-add-aroD. A deletion covering man-uidA-add was obtained. The gene gsk encoding guanosine kinase was cotransducible with purE and shown to be located at 13 min. The gene hpt encoding hypoxanthine phosphoribosyltransferase was cotransducible with tonA indicating a location at 3 min. The location of the gene gpt encoding guanine (xanthine) phosphoribosyltransferase in the proA-proB region was confirmed.

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