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Localization of two mouse genes encoding the protein tyrosine kinase receptor-related protein RYK

✍ Scribed by N. M. Gough; S. Rakar; C. M. Hovens; A. Wilks


Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
210 KB
Volume
6
Category
Article
ISSN
0938-8990

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✦ Synopsis


We have mapped the gene encoding the murine RYK growth factor receptor protein tyrosine kinase by genetic linkage analysis with recombinant inbred strains of mouse. Two distinct Ryk loci (Ryk-1 and Ryk-2) were identified. Ryk-1 mapped to Chromosome (Chr) 9, whereas Ryk-2 mapped to Chr 12. A similar


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## Abstract Two alternatively spliced variants of an orphan __Caenorhabditis elegans__ G‐protein‐coupled receptors (GPCRs; Y58G8A.4a and Y58G8A.4b) were cloned and functionally expressed in Chinese hamster ovary (CHO) cells. The Y58G8A.4a and Y58G8A.4b proteins (397 and 433 amino acid residues, res