Localization of the CDKN4/p27Kip1gene to
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Emmanuel Martin; Valère Cacheux; Hélène Cavé; Jean Michel Lapierre; Denis Paslie
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Article
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1995
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Springer
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English
⚖ 774 KB
CDKN4/p27Kip1 is a cyclin-dependent kinase (Cdk) inhibitor implicated in G1 phase arrest, which negatively regulates G1 phase progression in response to TGF beta, and might represent a tumor suppressor gene. We report here the chromosomal assignment of the human CDKN4 gene to chromosome 12p12.3 in c