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Localization of the iron-regulatory proteins hemojuvelin and transferrin receptor 2 to the basolateral membrane domain of hepatocytes

✍ Scribed by Uta Merle; Franziska Theilig; Evelyn Fein; Sven Gehrke; Birgit Kallinowski; Hans-Dieter Riedel; Sebastian Bachmann; Wolfgang Stremmel; Hasan Kulaksiz


Publisher
Springer
Year
2006
Tongue
English
Weight
402 KB
Volume
127
Category
Article
ISSN
1432-119X

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p105CasL (CasL) is a recently identified signaling molecule closely related to the p130Cas (Crk-associated substrate) docking protein. CasL has a single Src homology (SH) 3 domain in its N-terminal portion followed by multiple consensus motifs for binding to SH2 domains. Like original p130Cas, CasL