In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation

Localization of the iron transport prote

Localization of the iron transport proteins mobilferrin and DMT-1 in the duodenum: The surprising role of mucin

✍ Marcia Simovich; Lucille N. Hainsworth; P.A. Fields; Jay N. Umbreit; Marcel E. C 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 824 KB

Alterations in the expression of the cel

Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma : Relation to p27Kip1 and its Ubiquitin Ligase Subunit, S Phase Kinase Protein 2

✍ Ma'anit Shapira; Ofer Ben-Izhak; Bishara Bishara; Boris Futerman; Ira Minkov; Mi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 2 views

## Abstract ## BACKGROUND Low levels of p27^Kip1^ are associated with high aggressiveness and poor prognosis in various malignancies, including colorectal carcinoma. The authors showed that S phase kinase protein 2 (Skp2), the specific ubiquitin ligase subunit that targets p27^Kip1^ for degradatio

Genomic organization and chromosomal loc

Genomic organization and chromosomal localization of the human CUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma development

✍ Steven C. Clifford; Sally Walsh; Katie Hewson; Elaine K. Green; Astrid Brinke; P 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB 👁 2 views

Germline mutations in the von Hippel-Lindau (VHL) disease tumor suppressor gene (TSG) convey a high risk of clear-cell renal-cell carcinoma (CC-RCC) and most sporadic CC-RCCs demonstrate somatic inactivation of the VHL TSG. However, the existence of further CC-RCC gatekeeper genes is implied by CC-R

Do multidrug resistance-associated prote

Do multidrug resistance-associated protein-1 and -2 play any role in the elimination of estradiol-17β-glucuronide and 2,4-dinitrophenyl-S-glutathione across the blood–cerebrospinal fluid barrier?

✍ Young-Joo Lee; Hiroyuki Kusuhara; Yuichi Sugiyama 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB

The purpose of this study was to examine the role of multidrug resistanceassociated protein-1 and -2 (Mrp1 and Mrp2) in the efflux transport of organic anions across the blood-cerebrospinal fluid (CSF) barrier. The CSF concentration of estradiol-17b-glucuronide (E 2 17bG) and 2,4-dinitrophenyl-S-glu

B and T lymphocyte subsets enter periphe

B and T lymphocyte subsets enter peripheral lymph nodes and Peyer's patches without preference in vivo: no correlation occurs between their localization in different types of high endothelial venules and the expression of CD44, VLA-4, LFA-1, ICAM-1, CD2 or L-selectin

✍ Jürgen Westermann; Yutaka Nagahori; Sebastian Walter; Catharina Heerwagen; Masay 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

B and T lymphocyte subsets enter peripheral lymph nodes and Peyer's patches without preference in vivo: no correlation occurs between their localization in different types of high endothelial venules and the expression of CD44, VLA-4, LFA-1, ICAM-1, CD2 or L-selectin\* Many lymphocytes enter tissues