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Localization of the human coproporphyrinogen oxidase gene to chromosome band 3q12

✍ Scribed by Valère Cacheux; Pavel Martasek; Françoise Fougerousse; Marie Hélène Delfau; Luc Druart; Gerard Tachdjian; Bernard Grandchamp

Publisher
Springer
Year
1994
Tongue
English
Weight
508 KB
Volume
94
Category
Article
ISSN
0340-6717

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✦ Synopsis

The human gene encoding coproporphyrinogen oxidase is the defective gene in hereditary coproporphyria. This gene was mapped to chromosome band 3q12 using fluorescent in situ hybridization. The chromosomal localization was confirmed by cosegregation of the human gene with chromosome 3 in a panel of human/rodent somatic hybrids.

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