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Regional localization of human M-BCR gene to chromosome 23 band q11 in the great apes

✍ Scribed by Rhea V. Samonte; K. H. Ramesh; Ram S. Verma

Publisher: Springer Netherlands
Year: 1996
Tongue: English
Weight: 150 KB
Volume: 98
Category: Article
ISSN: 0016-6707
DOI: 10.1007/bf00120226

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✦ Synopsis

We hybridized a human M-BCR DNA probe to the chromosomes of chimpanzee (Pan troglodytes), gorilla (Gorilla gorilla) and orangutan (Pongo pygmaeus) by FISH-technique. The human M-BCR gene was localized to chromosome 23 band ql 1 (23ql 1), which is equivalent to the human chromosome 22 band ql 1 in all three species. The conservation of M-BCR gene in higher primates at the corresponding human chromosome locus provides phylogenetic clues concerning the evolution of genes.

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