Localization of the enzyme 3-deoxy-d-manno-2-octulosonic acid aldolase
โ Scribed by Bernd Richard Knappmann; Maria-Regina Kula
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 518 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1432-0614
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๐ SIMILAR VOLUMES
## Abstract [(Benzyloxy)(benzyloxycarbonyl)methyl]triphenylphosphonium bromide (8), obtained from glyoxylic acid via a convenient oneโpot procedure, reacted in a Wittig reaction with 4โ__O__โbenzylโ2,3:5,6โdiโ__O__โisopropylideneโDโmannose (7), readily synthesized on a large scale from Dโmannose, t
Acylation of ammonium 3-deoxy-n-D-manno-Z-octulopyranosonate (la) leads to the formation of peracetylated 3-deoxy-a-D-manno-2-octulopyranosono-1,5-lactones (3a,b). The proposed structures were confirmed by independent syntheses. The 1,7-lactone was not formed even when only OH-7 was available for la
KDO (1) is synthesized in five steps, starting from 1,2-to the carbonate 9. Silicon-induced lactonization affords the lactone 10, which can be converted into NH 4 -KDO by anhydro-3,4:5,6-di-O-isopropylidene-D-mannitol ( 6). The epoxide 6, obtained from D-mannitol (2), reacts with lithiated standard