Precise localization on chromosome 12 of
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C. Desmaze; J. Zucman; O. Delattre; T. Melot; G. Thomas; A. Aurias
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Article
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1994
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Springer
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English
⚖ 197 KB
The ATF-1 gene encodes for a transcription factor normally regulated by cAMP (Hai et al. 1989, Yoshimura et al. 1990). Recently, it has been shown to be involved in the recurrent t(12;22) translocation observed in soft tissue malignant melanoma, in a fusion gene with the EWS gene (Zucman et al. 1993