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Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity

✍ Scribed by Yuko Kojima; Akemi Kawasaki-Koyanagi; Noriyoshi Sueyoshi; Atsushi Kanai; Hideo Yagita; Ko Okumura


Book ID
117052311
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
390 KB
Volume
296
Category
Article
ISSN
0006-291X

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The Fas/Fas-ligand (Fas-L) system is involved in the induction of apoptosis and mediates T-cell cytotoxicity. We investigated the Fas/Fas-L system and cytotoxic T lymphocytes (CTLs) in 30 lymphoepithelioma-like cancer of the stomach (LECS) in order to understand the immune evasion of the tumor cells