Previously we reported results of an incubation experiment with neurofilaments that supported the existence of a p-type of Ca2+-activated neutral protease in the rat peripheral nerve; it was active with pM order Ca2' (p-CANP). This time, we partially purified the p-CANP from a crude CANP fraction of
Localization of calcium-activated neutral protease (CANP) in the peripheral nerve
โ Scribed by Drs. Keiko Kamakura; Drs. Shoichi Ishiura; Dr. Takehisa Fujita; Drs. Ikuya Nonaka; Drs. Hideo Sugita
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 268 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0148-639X
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There are two types of calcium-activated neutral protease (CANP), m-CANP and p-CANP, following the nomenclature of Suzuki et a1 to show that each requires mM and pM Ca2+, respectively, for its activation. We found p-CANP activity in a crude CANP fraction extracted from the peripheral nerve, which de
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