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Localization by in situ hybridization of three 3p probes with respect to the breakpoint in a t(3;8) in hereditary renal cell carcinoma

✍ Scribed by Annemarie H. van der Hout; Robert S. Brown; Frederick P. Li; Charles H.C.M. Buys


Book ID
119104801
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
219 KB
Volume
51
Category
Article
ISSN
0165-4608

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In a loss of heterozygosity analysis of 3p, we examined 44 sporadic cases of renal cell carcinoma (RCC) and matched normal tissue with 18 markers distributed over the whole p-arm. The majority of these markers clustered in three regions that have been suggested t o be involved in the development of