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Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear

✍ Scribed by Thomas, Paul V.; Cheng, Andrew L.; Colby, Candice C.; Liu, Liqian; Patel, Chintan K.; Josephs, Lydia; Duncan, R. Keith


Book ID
122145039
Publisher
Elsevier
Year
2014
Tongue
English
Weight
675 KB
Volume
103
Category
Article
ISSN
1874-3919

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## Abstract The Na^+^/H^+^ exchanger 1, which plays an essential role in intracellular pH regulation in most tissues, is also known to be a key actor in both proliferative and apoptotic processes. Its activation by H^+^ is best described by the Monod–Wyman–Changeux model: the dimeric NHE‐1 oscillat