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Localization and phototoxic effect of zinc sulfophthalocyanine photosensitizer in human colon (DLD-1) and lung (A549) carcinoma cells (in vitro)

โœ Scribed by Sello Lebohang Manoto; Palesa Rose Sekhejane; Nicolette Nadene Houreld; Heidi Abrahamse

Book ID
116823443
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
787 KB
Volume
9
Category
Article
ISSN
1572-1000

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โœ Tracey D. Bradshaw; Andreas Gescher; George R. Pettit ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 711 KB

I 2-0-tetradecanoylphorbol-I 3-acetate (TPA) and bryostatin I are activators of protein kinase C (PKC). TPA is a potent inhibitor of the growth of A549 cells, while bryostatin I exerts a weak antiproliferative effect upon this cell line. We tested the hypothesis that the PKC inhibitor staurosporine