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Localization, Anchoring, and Functions of Protein Kinase C Isozymes in the Heart

โœ Scribed by Katrina Mackay; Daria Mochly-Rosen


Book ID
115633265
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
105 KB
Volume
33
Category
Article
ISSN
0022-2828

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A calcium-sensitive, phospholipid-dependent protein kinase (protein kinase C) and its three isozymes were purified from rat heart cytosolic fractions utilizing a rapid purification method. The purified protein kinase C enzyme showed a single polypeptide band of 80 KDa on SDS-polyacrylamide gel elect