Localisation of the Penicillinase Gene in Naturally Occurring Staphylococcus Aureus Strains
โ Scribed by Rosdahl, Vibeke Thamdrup
- Book ID
- 114822094
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Weight
- 491 KB
- Volume
- 93B
- Category
- Article
- ISSN
- 0108-0180
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As shown by BARBER (1949), FAIRBROTHER, PARKER and EATON (1954), BONDI, KORNBLUM and de SAINT PHALLE (1953) and other authors, penicillinase-positive Xtaphylococczcs aureus strains may frequently give rise to penicillinase-negative mutants. BOROWSKI (1963a) found that ability to produce penicillinas
Mutant penicillinase plasmids, in which penicillinase synthesis is not inducible by penicillin or a penicillin analogue, were examined by biochemical and genetic analyses. In five of the six mutants tested, penicillinase synthesis could be induced by growth in the presence of 5-methyltryptophan. It