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Localisation and pharmacological characterisation of D-2 dopamine receptors in rat cerebral neocortex and cerebellum using [125I]iodosulpride

✍ Scribed by Marie-Pascale Martres; Nicole Sales; Marie-Louise Bouthenet; Jean-Charles Schwartz

Book ID
115879044
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
905 KB
Volume
118
Category
Article
ISSN
0014-2999

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## Abstract Iodobenzamide (IMB) labeled with either [^11^C] or [^125^I] was studied in mice and baboons. Pharmacological studies demonstrated an in vivo binding profile compatible with D~2~ dopamine receptors. Mouse biodistribution studies with both [^11^C]IMB and [^125^I]IMB showed a similar brain