Local Protein Surface Patch Method for Protein-Ligand Binding Prediction
β Scribed by Sael, Lee; Kihara, Daisuke
- Book ID
- 122137807
- Publisher
- Biophysical Society
- Year
- 2011
- Tongue
- English
- Weight
- 38 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0006-3495
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A new, fast, and easy-to-implement method, van der Waalsαfast Ε½ . Fourier transform vdW-FFT , for locating possible binding sites on the surface of a protein was developed and tested on a set of 15 different enzymeαligand complexes. The method scans the whole protein surface and possible ligand orie
## Abstract In this study, a novel method was developed to predict the binding affinity of proteinβligand based on a comprehensive set of structurally diverse proteinβligand complexes (PLCs). The 1300 PLCs with binding affinity (493 complexes with __K__~d~ and 807 complexes with __K__~i~) from the