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Constructing patch-based ligand-binding pocket database for predicting function of proteins

✍ Scribed by Lee Sael; Daisuke Kihara


Book ID
119894331
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
779 KB
Volume
13
Category
Article
ISSN
1471-2105

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Accurately predicting the binding affinities of large sets of protein-ligand complexes efficiently is a key challenge in computational biomolecular science, with applications in drug discovery, chemical biology, and structural biology. Since a scoring function (SF) is used to score, rank, and identi