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A Comparative Assessment of Ranking Accuracies of Conventional and Machine-Learning-Based Scoring Functions for Protein-Ligand Binding Affinity Prediction

โœ Scribed by Ashtawy, Hossam M.; Mahapatra, Nihar R.


Book ID
117908630
Publisher
IEEE
Year
2012
Tongue
English
Weight
853 KB
Volume
9
Category
Article
ISSN
1545-5963

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A Comparative Assessment of Ranking Accu
โœ Ashtawy, Hossam M.; Mahapatra, Nihar R. ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› IEEE ๐ŸŒ English โš– 853 KB

Accurately predicting the binding affinities of large sets of protein-ligand complexes efficiently is a key challenge in computational biomolecular science, with applications in drug discovery, chemical biology, and structural biology. Since a scoring function (SF) is used to score, rank, and identi