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Local destabilisation of a DNA double helix by a T–T wobble pair

✍ Scribed by Cornelis, A. G.; Haasnoot, Jeroen H.J.; den Hartog, Jan F.; de Rooij, M.; Boom, Jacques H. van; Cornelis, Altona

Book ID: 109716169
Publisher: Nature Publishing Group
Year: 1979
Tongue: English
Weight: 219 KB
Volume: 281
Category: Article
ISSN: 0028-0836
DOI: 10.1038/281235a0

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## Abstract In‐phase ligated DNA containing T~__n__~A~__n__~ segments fail to exhibit the retarded polyacrylamide gel electrophoresis (PAGE) migration observed for in‐phase ligated A~__n__~T~__n__~ segments, a behavior thought to be correlated with macroscopic DNA curvature. The lack of macroscopic