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Local bone formation by injection of recombinant human bone morphogenetic protein-2 contained in polymer carriers

โœ Scribed by N Saito; T Okada; H Horiuchi; H Ota; J Takahashi; N Murakami; M Nawata; S Kojima; K Nozaki; K Takaoka

Book ID
117807815
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
326 KB
Volume
32
Category
Article
ISSN
8756-3282

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Restoration of segmental bone defects in
Restoration of segmental bone defects in rabbit radius by biodegradable capsules containing recombinant human bone morphogenetic protein-2
โœ Mori, Masahiro ;Isobe, Masatsugu ;Yamazaki, Yasuharu ;Ishihara, Kazuhiko ;Nakaba ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 517 KB

Recombinant human bone morphogenetic protein-2 (rhBMP-2) was encapsulated in biodegradable poly(DL-lactide-co-glycolide) (PLGA) capsules to regenerate bone by controlling the release rate of rhBMP-2. The rhBMP-2/PLGA capsules containing 12 g of rhBMP-2 were implanted in seven 15-mm segmental defects