Restoration of segmental bone defects in
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Mori, Masahiro ;Isobe, Masatsugu ;Yamazaki, Yasuharu ;Ishihara, Kazuhiko ;Nakaba
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Article
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2000
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John Wiley and Sons
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English
β 517 KB
Recombinant human bone morphogenetic protein-2 (rhBMP-2) was encapsulated in biodegradable poly(DL-lactide-co-glycolide) (PLGA) capsules to regenerate bone by controlling the release rate of rhBMP-2. The rhBMP-2/PLGA capsules containing 12 g of rhBMP-2 were implanted in seven 15-mm segmental defects