Local and Systemic Effects of Intraduodenal Exposure to Topical Gallstone Solvents Ethyl Propionate and Methyl tert-Butyl Ether in the Rabbit

Increased blood levels of methyl tert-bu

Increased blood levels of methyl tert-butyl ether but not of ethyl propionate during instillation with contact gallstone dissolution agents in the pig

✍ Oliver Esch; Claudio D. Schteingart; Dirk Pappert; Diane Kirby; Rita Streich; Al 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 831 KB

We performed experiments in anesthetized piglets with two cholesterol gallstone solvents, methyl tertbutyl ether and ethyl propionate, to determine whether blood levels of either solvent would increase during gallbladder instillation of these solvents under conditions simulating gallstone dissolutio