𝔖 Bobbio Scriptorium
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LKB1 (XEEK1) regulates Wnt signalling in vertebrate development

✍ Scribed by Ossipova, Olga; Bardeesy, Nabeel; DePinho, Ronald A.; Green, Jeremy B. A.


Book ID
109912108
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
757 KB
Volume
5
Category
Article
ISSN
1465-7392

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Wnt signaling regulates many aspects of vertebrate development and adult stem cells. Deregulation of Wnt signaling causes development defect and cancer. The signaling is categorized in two pathways: canonical and noncanonical. Both pathways are initiated by Wnt ligands and Frizzled receptors. Canoni