sFRP-2 is a target of the Wnt-4 signalin
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Birgit Lescher; BΓ©nΓ©dicte Haenig; Andreas Kispert
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Article
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1998
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John Wiley and Sons
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English
β 612 KB
Members of the Wnt family of secreted glycoproteins act as short-range signaling molecules in vertebrate embryogenesis. Previous work has shown that Wnt-4 is required for kidney development. Mice lacking functional Wnt-4 fail to form pretubular cell aggregates. Wnt-4 acts as an autoinducer of the me