The aim of this prospective study was to assess the uptake of predictive genetic testing for hereditary non-polyposis colorectal cancer (HNPCC) and its associations with sociodemographic and other factors, and long-term satisfaction with taking the test. The test was offered to all high-risk members
Living with Hereditary Non-polyposis Colorectal Cancer; Experiences from and Impact of Genetic Testing
β Scribed by C. Carlsson; M. Nilbert
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 190 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1059-7700
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## Abstract We report the cytogenetic study of 9 colorectal tumors arising in patients with hereditary nonβpolyposis colorectal cancer (HNPCC). According to the cytogenetic classification of colorectal tumors previously proposed by us, 2 cases were of the trisomic type, 2 were of the monosomic type
Predictive genetic testing for cancer allows identification of those with the mutation (mutation positive) who should undergo cancer surveillance aiming at early detection of cancer and those without the mutation (mutation negative), whose unnecessary worry can be alleviated and who need not undergo