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Liver involvement in Langerhans cell histiocytosis

✍ Scribed by Adelaine Wong; Clara L. Ortiz-Neira; Walid Abou Reslan; Raphael Sharon; Alfredo Pinto-Rojas; Deepak Kaura; Ronald Anderson

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
196 KB
Volume
36
Category
Article
ISSN
0301-0449

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Background. Ear involvement (EI) in Langerhans' cell histiocytosis (LCH) occurs quite often. We reviewed the Italian pediatric population of 251 children with LCH diagnosed between 1982 and 1995, focusing on EI, to highlight the prevalence, the clinical presentation, the outcome during follow-up, an

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The characteristic cell type involved in Langerhans cell histiocytosis, 'LCH cells', express most of the enzyme histochemical and immunocytochemical markers of normal epidermal Langerhans cells. It is not known, however, whether these LCH cells express the functional characteristics of normal epider