Background. Ear involvement (EI) in Langerhans' cell histiocytosis (LCH) occurs quite often. We reviewed the Italian pediatric population of 251 children with LCH diagnosed between 1982 and 1995, focusing on EI, to highlight the prevalence, the clinical presentation, the outcome during follow-up, an
Congenital langerhans cell histiocytosis with isolated skin involvement
✍ Scribed by Schroth, Michael ;Hertzberg, Holger ;Langer, Thorsten ;Beck, J�rn Dirk
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 53 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0098-1532
- DOI
- 10.1002/mpo.1170
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Background. Manifestations of Langerhans cell histiocytosis (LCH) in children range from only a rash, to bony lesions accompanied by pain, to major organ disease. When the central nervous system (CNS) is affected, the LCH patient may exhibit signs and symptoms of hypothalamic and pituitary dysfuncti
## Abstract Langerhans cell histiocytosis (LCH) and malignancy occurring in the same individual is unusual and has generally been the subject of isolated case reports. To better define the occurrence of these events a registry of cases with synchronous or asynchronous LCH and malignancy was develop