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Liver cell carcinoma with osteoclast-like giant cells: Nonepitheliogenic giant cells in diverse malignancies

✍ Scribed by Juan Rosai

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
274 KB
Volume
12
Category
Article
ISSN
0270-9139

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✦ Synopsis

Hepatocellular carcinoma with osteoclast-like giant cells (hepatic giant cell carcinoma ([HGCC]) is a rare entity, with only three cases reported. The tumor is histologically similar to giant cell tumor (GCT) of bone, and the origin of the multinucleated giant cells and mononuclear stromal cells has not been determined. The purpose of this report is to present a case of this rare tumor and compare its ultrastructural and immunohistochemical features with those of a con- ventional GCT of bone. Histologically, the HGCC con-

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