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Liver Carcinogencsis by Methyl Carbamate in F344 Rats and Not in B6C3F1 Mice

โœ Scribed by Chan, Po C. ;Huff, James ;Haseman, Joseph K. ;Quest, John A. ;Hall, William


Book ID
118699774
Publisher
Wiley (Blackwell Publishing)
Year
1992
Tongue
English
Weight
396 KB
Volume
83
Category
Article
ISSN
0910-5050

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Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr